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The primary goal is to decrease the concentration or production of melanin, the pigment responsible for the color of the skin, hair, and eyes

Medical Science 43 (4), 668678

However, our studies showed that GCLC expression increased during the later part of the day and through to the dark period (2pm-6am) ( Figure 4B ), while GS and GR levels peaked at the start of the dark period ( Figures 4C, D )