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The neurotoxins 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or 6-hydroxydopamine (6-OHDA) specifically damage this brain region, resulting in the loss of dopaminergic neurons (156)

Some of these compounds (for example, verapamil) bind to the Pgp molecule and inhibit in a competitive manner the binding or transport of drugs that are Pgp substrates

Muscle-specific kinase myasthenia gravis

Mosaoa RM, Al-Rabia MW, Asfour HZ, Alhakamy NA, Mansouri RA, El-Agamy DS, Abdulaal WH, Mohamed GA, Ibrahim SRM, Elshal M (2024) Targeting SIRT1/AMPK/Nrf2/NF-B by sitagliptin protects against oxidative stress-mediated ER stress and inflammation during ANIT-induced cholestatic liver injury