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This powerful combination internally addresses dark spots, tanning, and pigmentation, resulting in brighter, radiant, and uniformly toned skin from head to toe

doi: 10.1177/014556130608500201 207 HanSTayJKLohCJLChuAJMYeongJPSLimCMet al

4.1 H-89 reduced PKA, p-CREB/CREB protein expression with PKA mRNA expression in thyroid tissue To verify the inhibitory effect of H-89 on the cAMP signaling pathway, WB was used to detect the protein expression levels of PKA and p-CREB/CREB in thyroid tissue, and RT-PCR was used to measure the mRNA expression level of PKA in thyroid tissue ( Figures 7AG )

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