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It is known to activate major cascades like PI3 kinase-AKT, RAS-RAF-MEK-ERK, and STATs cascades 35 , and has been hypothesized that it also activates the NFB signaling cascade 36 , which is a well-known inflammatory and oxidative stress pathway

2019 Mar 14;7(3):e2160

GIP is an incretin hormone that indirectly regulates glucagon secretion and increases glucose-stimulated insulin secretion [17]

Therapeutic doses of vitamin C may act against cancer development and progression through several other mechanisms, such as stimulating immune system activation or enhancing the chemosensitivity of cancer cells, but evidence beyond preclinical models is still lacking (124, 125)

Prediction of pulmonary embolism in the emergency department: the revised Geneva score