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Determination of oxidant/antioxidant capacity biomarkers Lipid peroxidation was measured using the thiobarbituric acid reactive substances (TBARS) assay by Tappel and Zalkin (1959)

Therefore, future efforts must prioritize the development of subset-selective metabolic modulators and the identification of metabolic biomarkers that predict which patients can leverage metabolic reprogramming to support durable AIM, thereby enabling metabolism-targeted personalized immunotherapy