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Macrophage polarization states in the tumor microenvironment

There is currently is evidence for high dosages of vitamin C in the general ICU population and guidelines uniformly recommend against the use of vitamin C in pharmacologic dosages (130, 131)

Thioredoxin system in insects: uncovering the roles of thioredoxins and thioredoxin reductase beyond the antioxidant defences

An initial study with a limited sample size (39 HAPE patients and 43 controls) revealed no role of CYBA in HAPE pathogenesis in Caucasians, 119 but a larger Indian cohort (150 HAPE patients and 180 controls) linked CYBA (rs4673 and rs9932581) and GSTP1 (rs1695 and rs1138272) to elevated circulating 8-iso-prostaglandin F2 in HAPE, potentially contributing to HAPE susceptibility

Hiroki Kitakata et al