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DePace specializes in the diagnosis and treatment of autonomic nervous system dysfunction (dysautonomia) , including POTS, autonomic dysfunction associated with Ehlers-Danlos syndrome (EDS) , chronic fatigue, and anxiety-like conditions that are frequently misdiagnosed

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Lovell, S

Market Restraining Factor Patient Recruitment and Retention Issues Patient recruitment and retention remain critical challenges in the clinical trial industry, significantly hindering the speed and success of drug development

Figure 4 9 Modern NPP therapies targeting non-neuronal cells As summarized in Tables 2 and 3 , although several drugs for managing NPP have received FDA approval or are recommended by clinical guidelines, most of which are repurposed from other therapeutic areas rather than specifically developed for NPP