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The criteria for liver injury were vacuolization of hepatocytes and pyknotic hepatocyte nuclei, activation of Kupffer cells, and enlargement of sinusoids

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When its dysfunctional, or stuck open, microbes from the large intestine (which contains a million times more bacteria than the small intestine) can migrate backward into the small intestine and set the stage for a bloom or overgrowth, which is SIBO

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