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In conclusion, although the potential for synergy between exercise and vitamin D in promoting healthy brain aging is biologically plausible and supported by select preclinical and epidemiological findings, current clinical evidence remains inconclusive

Our data showed that iron overload in CD11c + myeloid cells induced IL-6 production, which enhanced neutrophil infiltration into the liver and exacerbated tissue damage

[29] Mouse models with this mutation do not exhibit the classical mitochondrial vacuolation pathology seen in G93A and G37R ALS mice and unlike G93A mice, deficiency of the major mitochondrial antioxidant enzyme, SOD2, has no effect on their disease course

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Since human clinical trials are essentially nonexistent, the available data comes from anecdotal reports from the biohacking community