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Several studies have confirmed the ability of Erwinaze to reduce plasma glutamine levels and improve overall survival in patients with refractory AML [25]

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10.1016/j.it.2010.06.007 Trends Immunol

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440,441,442 This process can be viewed as a two-phase mechanism: initial senescence induction followed by immune-mediated clearance

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The short chain dehydrogenases family was also upregulated in day 2 spherules (maximum upregulation 10.27 fold, CIMG_09765)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 248.Putman C

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