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It is best to take Vitamin B12 in the morning, preferably on an empty stomach

[DOI] [PubMed] [Google Scholar] 116.Mittag T.W., Danias J., Pohorenec G., Yuan H.M., Burakgazi E., Chalmers-Redman R., Podos S.M., Tatton W.G

To ensure that higher scores reflected a better outcome, the raw data for the appearance and symptom scales were scored as follows: not at all = 4, a little = 3, quite a bit = 2, and very much = 1