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Sirtuin 1 and Sirtuin 3: physiological modulators of metabolism

doi: 10.1038/nri.2017.105 132

[21] used IR-822 as a fluorescent group because of its excellent tumor preferential aggregation and other characteristics

This creates a bottleneck: inflammatory signaling after tendon microdamage can't recruit sufficient repair cells, and nutrient delivery to the injury site is limited