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Traditional cancer vaccines rely on the identification, selection, and ex vivo formulation of a limited set of tumor-specific neoantigens with immunological adjuvants (e.g., peptides, proteins, RNA, DNA)

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"Some of the side effects we found, like nausea, are well known, and that shows that the method is picking up a real signal," says Sharath Chandra Guntuku, Research Associate Professor in Computer and Information Science (CIS) at Penn Engineering and the study's senior author