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Details of the test used are given in the corresponding figure legends and the Source Data

Among these, cigarette smoke (CS) is the major risk factor for the development of COPD, which accounts for at least 75% of the deaths (Gong et al., 2019)

Semaglutide has been shown to provide impressive weight loss of around 1517% in clinical trials, whereas tirzepatide can potentially deliver slightly higher percentages