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In fact, animal models of SARS have been developed to recapitulate these findings

10.1002/jnr.22132 126 La FleurM.UnderwoodJ

The preferred first-line opioids are: hydromorphone at low doses (1 mg oral or 0.4 mg intravenous) or oxycodone (2.5 mg oral) with more extended dose intervals, as well as intravenous fentanyl in hospitalized patients or patches in outpatients