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Corsini EM, Mitchell KG, Zhou N, Antonoff MB, Mehran RJ, Mena GE, Rajaram R, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC, Hofstetter WL

Cell Stem Cell 26 , 722738 (2020)

Important Safety Considerations Cardiovascular Risks : Average increase in heart rate: 5-10 bpm Blood pressure elevation: 5-10 mmHg systolic Contraindicated in patients with structural cardiac abnormalities Neuropsychiatric Effects : Risk of anxiety, insomnia, and irritability Potential for exacerbating tic disorders Rare cases of psychosis at high doses The Reality of Off-Label Use for Weight Loss While some providers prescribe Adderall off-label for weight management, several concerns exist: Lack of Long-Term Data : No studies support its efficacy beyond 6 months for weight loss

Approximately 2% of the oxygen consumed by the mitochondria is converted into superoxide, making it one of the largest sources of endogenous ROS (19)

Remember, things that make muscle grow, like high IGF1, 2, 3 and 4 levels also make cancer cells grow more rapidly