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Secondly, in order for the mechanism to come into place, natural populations should contain a significant fraction of old individuals, which is not observed either (Williams, 1957). This statement was the basis not just of Williamss 1957 theory, but more explicitly of the Medawar theory 5 years earlier

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Patients with Babesia and Lyme Disease often experience significantly more severe disease and worse outcomes than those experiencing a single infection (15, 16, 17)

Skp2 is targeted for degradation by the Anaphase Promoting Complex/Cyclosome during G1-phase of the cell cycle [48, 49]

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