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Reactive astrocytosis is a consistent pathological hallmark not only in AD, but also in PD, ischemic stroke, and ALS

Neufeld EJ, Galanello R, Viprakasit V, Aydinok Y, Piga A, Harmatz P, et al

Integrated analysis of genetic alterations in signalling pathways across 33 cancer types from The Cancer Genome Atlas (TCGA) revealed that GBM had a frequency of 86% in cell cycle, 77% in receptor-tyrosine kinase (RTK)/rat sarcoma (RAS), 57% in phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K), and 48% in p53 pathways [49]