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Additionally, transcriptomic reprogramming in DTPs weakens the mitogen-activated protein kinase (MAPK) dependence, while enhancing reliance on multi-receptor tyrosine kinases (RTKs) and PD-L2, enhancing the cellular features of mesenchyme, angiogenesis and IFN-inflammation [70]

The peptide effectively reversed the muscle strength decrease caused by glucocorticoid treatment

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Under oxidative stress, excessive ROS emissions lead to mitochondrial damage, and loss or defects in mitochondrial energy production can enhance metabolic processes in the tricarboxylic acid (TCA) cycle, ETC, exacerbating ROS release and reducing antioxidant enzymes [81,82,83]