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These findings suggest that SZRD may alleviate AD-related neuronal damage, synaptic dysfunction, and ferroptosis by activating the DJ-1/Nrf2 signaling pathway

Libraries for the SC- cell stage scRNA-seq were prepared using the 10xGenomics kit following the manufacturers protocol

Minor irritation or early-stage ulcers may respond more quickly, while chronic conditions, severe ulcers, or extensive tissue injury require longer periods for repair

Proteostatic pathways are deregulated in middle-aged and aged Mda5 -/- HSCs To investigate the molecular mechanism underlying the youthful phenotype of Mda5 -/- HSCs, we performed bulk RNA-sequencing (RNA-seq) to compare young, middle-aged, and aged WT and Mda5 -/- HSC transcriptomes

Tangles have a higher association with AD than plaques do