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In addition, hBMSCs treatment was found to be safe, with no tumor formation observed in mice after injection and no detectable integration of human DNA into the offspring genome [124]

The process of acetylation shields the thiol group from oxidation prior to absorption, ensuring that once inside the cell, S-Acetyl-L-glutathione is hydrolyzed by cytoplasmic thioesterases, thereby replenishing the intracellular GSH pool