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1.4 P62-dependent Nrf2 Regulation Additional pieces of evidence suggest that other regulators also may activate the Nrf2 pathway

261,262,263 Cuproptosis as a putative therapeutic target for Wilsons disease As mentioned above, mutations in the ATP7B gene, which encodes the Cu-transporting P-type ATPase ATP7B, are associated with Wilsons disease, a life-threatening disorder in which patients present with progressive Cu accumulation in several tissues, particularly the liver, brain, and cornea

Chernausek SD, Backeljauw PF, Frane J, Kuntze J, Underwood LE, Group GHISC: Long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity

Stability in solution is finite

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