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Description

Int J Mol Sci 23:3779

Oral versions exist, but injections generally provide better absorption and effectiveness

BMC Anesthesiol 2022, 22: 165

Although ApoE does not cross the bloodbrain barrier (BBB), it is abundantly expressed in the central nervous system (CNS) by astrocytes, microglia, vascular mural cells, and choroid plexus cells, and to a lesser extent in stressed neurons (Boyles et al., 1985