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ROS-related anticancer mechanisms include mitochondrial dysfunction, p53-dependent apoptosis, iron-dependent ferroptosis, activation of endoplasmic reticulum stress, inhibition of growth signaling pathways (such as the epidermal growth factor pathway, EGF), among others

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Mucuna pruriens Mucuna pruriens, a leguminous plant rich in L-DOPA, directly replenishes central dopaminergic tone, an upstream regulator of VIP secretion from hypothalamic and limbic neurons

Strohecker AM, et al