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In summary, exosomes from various nerve cell sources contribute to post-SCI repair by carrying specific miRNAs or proteins that act on distinct cellular targets and signaling pathways

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Indeed, Yun and co-workers found that the intracellular reduction of DHA back to vitamin C depleted the cellular stores of reduced glutathione (GSH, the major antioxidant in cells), leading to an increase in reactive oxygen species (ROS)

Some have barely been tested in humans at all

Given that no trial has established what the ratio should be, that permanence encodes a manufacturers guess rather than a finding