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Description

Histamine is primarily metabolized via methylation and Phase 2 liver detoxification, both of which are heavily dependent on adequate glutathione availability

10.1016/s0006-8993(98)01192-5 26 BrownT

PMC 2928224

SFB vector was used as a negative control

Treatment of rats with monocrotaline, a pyrrolizidine alkaloid, was also shown to increase the activity of GS to a comparable level as that of GCL (Yan and Huxtable, 1996)