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The research published on Karger [1] showed that obese Zucker rats treated orally with AOD 9604 had over 50% less body weight gain and increased lipolytic activity

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Consistent with these results, mouse embryonic fibroblasts (MEFs) lacking the clock activator Bmal1 displayed reduced CI respiration, whereas MEFs lacking the repressors Cry1 and Cry2 exhibited increased CI respiration (Fig

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Funding This work was supported by the NWO (Dutch Research Council) Veni Fellowship [grant number 09150161810102]