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Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome PMC Oral Melanotic Macule: a small dark spot in the mouth ArtSmiles Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown A Black Spot on the Upper Gum for Many Years: Melanotic Macule Springer Nature Link melanotic macule gums Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview
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