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In addition, endothelial cells are involved in angiogenesis and mediate crosstalk between fibroblasts and various immune cells, and this crosstalk modulates fibroblast responses and the inflammatory and reparative microenvironment [163]

At 33.33 mg/mL, each injection equals 6 U-100 units (0.06 mL) , for approximately 6 mg per week [18]

For best results take on an empty stomach with 8 oz glass of water or as directed by your healthcare provider

That is intentional: the two vial sizes reflect two different documented protocols and two different concentration setups, and it is a reminder never to eyeball a dose across vial sizes

While promising, the doses required for sublingual delivery and the optimal formulation remain less established than injectable protocols