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"Paramutation: from maize to mice"

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Although these results appear to contradict previous studies reporting ROS-induced M1 macrophage polarization, they actually reveal the dual role of mtROS under varying dosages and immune environments

Given the established role of IL-4 in driving immune evasion in OvCa, IL-4R blockade may represent a promising strategy to overcome resistance to immunotherapy, particularly when combined with anti-PD-1 therapy

Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E