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In yet another study, researchers found that cigarette smoke prevented glutathione from reducing, therefore preventing it from performing its antioxidant duties as the reduced form of glutathione is the active form

Overall, the protein abundance log 2 ratios displayed a moderate correlation between S/P and S/Q ( R 2 =0.574), with 428 proteins (14.5%) significantly upregulated (log 2 S/P, S/Q1.5) and 475 (16.2%) downregulated (log 2 S/P, S/Q1.5)