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Pen Dosage Chart Dosage & Protocols Variations Standard Research Protocol Dose: 2 5 mg (= 410 clicks) Duration: 2 4 weeks Frequency: Daily Cycle Interval: 2-week pause Goal / Description: Used for baseline collagen and regeneration studies

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The CUMS-resistant rats were screened using behaviour tests (sucrose preference test (SPT), open field test (OFT) and light/dark test (LDT)) after 8 weeks of exposure to CUMS