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While these findings are promising, the complexity of human neurodegenerative diseases and the limitations of animal models necessitate cautious interpretation pending clinical validation

If the answer to any of these raises concerns, a fresh vial may be warranted

While several molecular effectors that control the specification of axons, including PI3-kinase, PTEN, GSK3, the Par family of proteins and the SAD kinases (Barnes et al., 2011) have been characterized, much less is known about how dendrite specification is achieved

Verify the solution has reached room temperature before adding solvent