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Thus, effective KRAS-targeted therapies must account not only for the biochemical consequences of specific point mutations but also for isoform-specific structural and functional differences

Lipid metabolism and lipid droplets Mitochondrial dysfunction impairs -oxidation of fatty acids, leading to lipid droplet accumulation within astrocytes

Cupping therapy may enhance efficacy when used as an adjunctive therapy but should be used with caution (215)

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AtD and wound healing are two areas of particular interest where studies have identified potential targets and mechanisms for TQs beneficial effects