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Routine Screening for At-Risk Individuals Regular health check-ups and blood tests can help detect B12 deficiency early, particularly in older adults, people with chronic digestive issues, or those on long-term medications that affect absorption

Importantly, both Clc treatmentsparticularly Clc 1:380prevented gliadin-induced increases in auto-Abs across multiple contexts, including anti-gliadin IgA and IgG in plasma and gut wash from males and females, and anti-TG2 IgA in plasma from females

We thank Dirk Schnappinger and Sabine Ehrt (Weill Cornell Medical College, New York) for kindly providing the cloning vectors used in the Gateway assembly of the Rv1127c expression plasmid