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Inhibiting TGF- could reduce fibrosis but may interfere with its protective roles in resolving inflammation and promoting tissue repair, leading to unintended consequences.93 94 Therefore, therapeutic approaches targeting TGF- must be carefully considered and finely tuned to balance its profibrotic and anti-inflammatory effects

Metformin is typically administered orally, in the form of tablets or capsules

Determination of Malonyl-CoA and Adenosine Triphosphate Levels in Rat Cardiac Tissue Using HPLC Malonyl-CoA and adenosine triphosphate levels were determined in heart tissues using HPLC system (Jasco Corporation, Ishikawa-Cho, Hachioji, Tokyo, Japan) According to Lysiak et al

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Urinary dimethylamine (DMA) and its precursor asymmetric dimethylarginine (ADMA) in clinical medicine, in the context of nitric oxide (NO) and beyond