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Zinc is known to benefit the skin and aloe vera is also a common skin soother, whilst Vitamin A is known as "ingestible retinol"

However, hormone therapy, while having a better therapeutic effect, is also associated with a certain risk of side effects, so it has to be applied appropriately and may not be suitable for all patients, and therefore researchers are currently exploring alternative treatments

Finally, soluble intra and extracellular forms of CD38 have also been described (Figure 3)[38-39, 57]

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The accumulation of sorbitol in the ocular tissue, for example, contributes to the development of diabetic cataracts (Figure 4)