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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Ambroxol as a disease-modifying treatment to reduce the risk of cognitive impairment in GBA-associated Parkinson's disease: a multicentre, randomised, double-blind, placebo-controlled, phase II trial

Gene expression and metabolic profiles revealed that mTORC1 activation causes a significant upregulation of the oxidative PPP by elevating the activity of the transcription factor sterol regulatory element-binding protein (SREBP) 48

36 (5), E49E60

Lencer (Boston Childrens Hospital, Harvard Medical School and Harvard Digestive Diseases center, United States) were cultured in MCDB 131 medium (Gibco) supplemented with 10% (v/v) heat-inactivated fetal bovine serum (FBS) (Gibco), 2 mM l-glutamine (Gibco), 25 g/mL streptomycin (Gibco), 25 U/mL penicillin (Gibco), 10 ng/mL recombinant mouse epidermal growth factor (Gibco), and 1 g/mL hydrocortisone (Sigma-Aldrich), at 37 C in a humidified atmosphere of 5% CO 2

Chanson, P