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10.1161/01.cir.102.16.1931 51 MinnitiC

et al., 2017), The Continuous Stroke Surveillance Program in 31 Chinese provinces reported an annual increase of 8.3% in the incidence of first stroke in adults, from 189 cases per 100,000 people in 2002 to 379 cases per 100,000 people in 2013with the incidence of ischaemic stroke and hemorrhagic stroke at 335 per 100,000 population and 44 per 100,000 population, respectively, in 2013 (He et al., 2022)

Additionally, they can also achieve anti-inflammatory function by inhibiting NF-B pathways and participating in immune regulation [169] (Table 1)

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This is particularly relevant for medications with narrow therapeutic windows