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This strategy is commonly used in site-specific cross-linking with bis or tri-electrophilic linkers and has proven to be a powerful method for reinforcing protein secondary and tertiary structures 37,38

Therefore, ubiquitination is not only important for protein degradation, but is also implicated in non-proteolytic functions, such as endocytosis, protein-protein interaction, intracellular trafficking, inflammatory signaling, autophagy, and DNA repair (Grabbe et al., 2011

Mechanisms of homocysteine-induced damage to the endothelial, medial and adventitial layers of the arterial wall

Effects of altering dietary fatty acid composition on prostaglandin synthesis and fertility

CagriSema, as of mid-2026, has no marketing approval from the FDA, the EMA, or any other regulator