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A study that compared 24 obese patients with MC-4R deficiency to 80 healthy controls (40 obese and 40 lean) found that those with MC-4R mutations consumed significantly more high-fat meals

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In vivo antitumor evaluation of Gi-F-CAA in EJ xenograft model Female BALB/c nude mice (~8 weeks, 18 g) were subcutaneously inoculated with 5 10 6 EJ cells resuspended in Matrigel

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Thus, the present results suggested that allicin may inhibit astrocyte apoptosis by increasing GPX1 expression