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They were subsequently randomly allocated into five groups, receiving different treatment regimen including: (I) PBS, (II) Mn/TI@mHSA, (III) P-Mn@mHSA, (IV) P-Mn/TI@mHSA-N, and (V) P-Mn/TI@mHSA, combined with a high-fat diet for an additional month

In addition, the analysis of human prostate cancer and prostate control specimens confirmed the aberrant expression of miR-124-3p, miR-129-5p, and miR-378 in primary tumors