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Scientists have posited that " the presence of a GHK triplet in the alpha 2(I) chain of type I collagen suggests that the tripeptide might be liberated by proteases at the site of a wound and exert in situ healing

Over the past several decades, DSIP has been studied for its potential to modulate sleep cycles, reduce stress, support hormonal balance, and enhance physical recovery

SRGN encodes for a proteoglycan in hematopoietic cells 26 and its overexpression is associated with poor prognosis in hepatocellular 50 , colorectal cancer 51 , non-small cell lung cancer 52 , and nasopharyngeal carcinoma 53

If the peptide structure has degraded, these mechanisms may not function at full capacity

Mast cells are powerful and rapid sensors of tissue injury/necrosis, infectious agents, and inflammation since they are located in the host-environment boundaries and express pattern recognition receptors and cytokines such as local alarmin, interleukin-33 (IL-33) (Martin and Martin, 2016)