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More broadly, gastrointestinal disorders that affect the small intestine (for example, ileal resection) could increase the risk of B 12 deficiency through malabsorption (Battat et al., 12 deficiency has been reported among untreated celiac disease patients (Theethira et al., 2014)

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The name comes from the GHK-Cu component, which is most associated with collagen production and skin-quality changes