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We also found a significant positive correlation between Trpa1 transcripts count with the Ucn1 and Cartpt mRNA levels, regardless the treatment conditions, further supporting a role for TRPA1 in regulating UCN1 and CART turnover 82 .The observed differences in the dynamics of UCN1 and CART despite their co-localization may suggest peptide-specific regulatory influence of TRPA1 however, further research is needed to unveil such mechanisms

Several enzymes involved in ATP production contain Fe-S clusters in the active site and are subject to similar inactivation by superoxide, including oxoglutarate dehydrogenase of the tricarboxylic acid cycle, as well as ETC complexes IIII