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All experimental procedures conformed to the Regulations for Animal Experiments and Related Activities at Tohoku University, were reviewed by the Institutional Laboratory Animal Care and Use Committee of Tohoku University, and were finally approved by the President of Tohoku University (#2019MdA-072, #2020MdA-139, #2021MdA-053)

Furthermore, we investigated whether VRK2 affects the transport of SLC7A11 by regulating ER-to-Golgi or Golgi-to-PM processes

Conflict of interest Author CS is employed by Differentia Biotech Ltd

Despite the high prevalence and the potential adverse impact on quality of life, there are currently no FDA-approved drugs specifically for treatment of tinnitus

According to ChemAnalyst, market pricing continues to be influenced by feedstock costs, manufacturing expenses, supply chain conditions, and downstream demand trends