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Thiols (R-SH), also known as mercaptans, are widely used in the synthesis of pharmaceuticals and agrochemicals due to their reactivity and versatility [9]

It also increases collagen III for tissue flexibility and drives collagen IV production up by a remarkable 25.4-fold when combined with hyaluronic acid

In CN tumor cells, MMP expression is downregulated in a Future strategies should consider a dual-targeted or stepwise approach to address both the tumor cells and the persistent ECM

108 This scenario could have serious clinical implications for organ transplant recipients who coincidentally have NF1, as these patients would have a drastically increased likelihood of developing malignant tumours on treatment with immunosuppressive drugs to prevent transplant rejection