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However, this idea, while demonstrating the ameliorative effect of vagus nerve excision on the association with obesity (101), is limited by the absence of significant changes in some lean animals and some populations (98), as well as the increased occurrence of secondary trauma and mortality after excision (102)

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10.1136/gut.2007.146290 31 Perez-TorresI.SotoM

6,23,57 Contributions of astroglia to neuropathology are however not limited to homoeostatic neuroprotection but can in some circumstances contribute to disorder progression

Moreover, senolytic efficacy of AD-MSCs therapy was observed in RAS-induced senescence in human and mouse kidneys