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10.1159/000480313 46 MouY.WangJ.WuJ.HeD.ZhangC.DuanC.et al (2019)

Effect of vitamin supplementation on polycystic ovary syndrome and key pathways implicated in its development: A Mendelian randomization study

This epigenetic silencing can lock T cells into an exhausted state and impair memory T cell differentiation, weakening long-term immunity ( 3.2.1Succinate Accumulation and HIF-1 Stabilization Damage to the ETC, particularly at Complex II (succinate dehydrogenase), can lead to the accumulation of succinate