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Following a one-week adaptation period, mice underwent five consecutive days of place navigation training in the MWM

GSK3, Glycogen synthase kinase-3-beta

ROS include free radicals such as superoxide ( O 2 - ), hydroxyl ( OH), peroxyl ( RO 2 ), hydroperoxyl ( HRO 2 - ) as well as nonradical species such as hydrogen peroxide (H 2 O 2 ) and hydrochlorous acid (HOCl) [8, 10]